The distribution and fate of iododeoxycytidine in the mouse and rat.
نویسندگان
چکیده
was incorporation of the radioactive label in the DNA extracted from various organs. In the rat, concentration of radioactivity in the DNA of each organ was appreciably higher at 24 hours than at 1 hour after injection and was increased at the latter interval by pretreatment with 5-fluorodeoxyuridine. Incorporation of ICdR into DNA of the rat was quantitatively less than that previ ously reported for bromodeoxycytidine (BCdR) and, except in the testis, less than that of lUdR. In the mouse the amounts of ICdR and lUdR incorporated into DNA were similar.
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عنوان ژورنال:
- Cancer research
دوره 22 شماره
صفحات -
تاریخ انتشار 1962